Utilizing single-molecule optical and AFM imaging and drive-spectroscopy approaches, we find to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our study pursuits involve:
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Deposition and atomic drive microscopy of unique phthalocyanine polymers in between nanofabricated electrodes
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Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
You're a Christian. If you may make such a artificial mobile, would you be one particular stage nearer to God, or would the function of God have diminished to some degree once again?
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2003, shown the 1st biosensors designed outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation
Pretty awesome, but that wasn’t seriously where my curiosity lay. I planned to pioneer And that i had the feeling which was now not possible, since the most appealing fundamental insights had by now been uncovered. But my area had made numerous enjoyable new resources to evaluate specific molecules. I made a decision which i wanted to use this to biology, to take a look at it from the Actual physical standpoint.’
In 1993 he was appointed as Associate Professor at Delft University of Engineering. During the mid-1990s Dekker and his crew reached success with the discovery of your Digital properties of carbon nanotubes, the primary one-molecule transistor and various nanoscience.
A lot of new phenomena had been discovered, and he and his exploration group recognized a leading posture In this particular field of exploration. Dekker and his analysis team identified new physics of nanotubes as well as explored the feasibility of molecular electronics. In 1998, they have been the very first to develop a transistor depending on only one nanotube molecule.
By way of example, we look at the nucleopore complex, a gateway concerning the mobile nucleus as well as the cytoplasm. This is a very sophisticated process and so hard to analyze in a very cell, so we use biomimetics. We reconstruct holes and then insert particular person factors from the nucleopore elaborate to review transportation by way of it at the single-molecule amount.’
At last, I'll briefly sketch some of our Tips to check out the making of artificial cells, precisely our first steps to establish synthetic ceesdekker cell division.