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Our group studies bacterial cell division and it is aiming to constitute a ‘base up biology’ in synthetic cells that will autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Management.
[Laughs] ‘It absolutely was definitely a great danger! At the time, I was well aware that it could go Completely wrong Which I could turn out to be much less effective, but I just ignored that. Curiosity has always been my strongest driving drive. And by chance all of it worked out.’
Given that 2000, Dekker has shifted the main emphasis of his do the job to biophysics wherever he reports the properties of single biomolecules and cells using the applications of nanotechnology. This alteration of area was pushed by his fascination with the outstanding operating of Organic molecular buildings, in addition to through the long-term viewpoint a large number of attention-grabbing discoveries can be anticipated In this particular subject.[five] Present-day lines of study in his biophysics group are within the regions of:[6]
That is a aspiration of mine and we set to work that has a scrumptious dose of naivety. This is certainly a thing that will probably produce amazing leads to the extended term, but that does not subject. You shouldn't only want to work within the issues of tomorrow, but also within the issues of the day soon after tomorrow.’
Microbiology has only existed for just a century, since we began to study micro-organisms much more significantly. I assumed nanobiology was an ideal time period, for the reason that all molecular Organic applicable interactions occur within the nanoscale: a protein is a few nanometres in size, DNA is 2 nm thick.’
‘Initially we checked out biological devices by using a physical perspective and acted on The idea of your resources we realized. It took a several years before we started off working additional on the large Organic challenges. I then began to contact it nanobiology, a phrase that did not exist at some time.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in gray, the rim with the pore is highlighted in red, as well as a 3D rendering of your movement on the DNA rod is shown.
Let's say, as opposed to using regular best-down silicon electronics, transistors could be created from The underside up working with single organic and natural molecules because the switching things? This idea, which grew to become The premise of nowadays’s field ceesdekker.net of molecular electronics, 1st emerged in the seventies.
But carbon nanotubes have remained a research subject matter of sizeable desire to lots of. In fact, the outlook on working with carbon nanotubes to develop functional units, in places like radio-frequency electronics, digital electronics and versatile electronics, stays brilliant.
Example (four) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of the pore is highlighted in pink, in addition to a 3D rendering with the motion of the DNA rod is exhibited.
Cees Dekker is Distinguished University Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Since 2000, he moved to single-molecule biophysics and nanobiology. His current research concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a living synthetic mobile from lifeless molecules. Dekker is really an elected member with the KNAW and fellow on the APS along with the IOP.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in crimson, in addition to a 3D rendering in the movement in the DNA rod is exhibited.